A fully joint Bayesian quantitative trait locus mapping of human protein abundance in plasma
نویسندگان
چکیده
منابع مشابه
Bayesian quantitative trait locus mapping using inferred haplotypes.
We describe a fast hierarchical Bayesian method for mapping quantitative trait loci by haplotype-based association, applicable when haplotypes are not observed directly but are inferred from multiple marker genotypes. The method avoids the use of a Monte Carlo Markov chain by employing priors for which the likelihood factorizes completely. It is parameterized by a single hyperparameter, the fra...
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The mapping of loci underlying variation in quantitative traits is proving to be a powerful tool in genetic studies of animals and other organisms. Quantitative trait locus (QTL) mapping in crosses between genetically diverse lines has shown the presence of many QTL, as similarly have studies within livestock populations. Although much remains to be done with this type of analysis, higher resol...
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Mendelian loci that control the expression levels of transcripts are called expression quantitative trait loci (eQTL). When mapping eQTL, we often deal with thousands of expression traits simultaneously, which complicates the statistical model and data analysis. Two simple approaches may be taken in eQTL analysis: (1) individual transcript analysis in which a single expression trait is mapped a...
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In this study 90 individuals of recombinant inbred lines (RILs) were developed by crossing subspecies of japonica rice cultivar, ‘Nagdong’ and an indica type cultivar, ‘Cheongcheong’. These individuals were used to identify the quantitative trait loci of panicle traits using SSR markers. A genetic linkage map was constructed using one hundred fifty four simple sequence repeat ...
متن کاملQuantitative trait loci mapping of panicle traits in rice
In this study 90 individuals of recombinant inbred lines (RILs) were developed by crossing subspecies of japonica rice cultivar, ‘Nagdong’ and an indica type cultivar, ‘Cheongcheong’. These individuals were used to identify the quantitative trait loci of panicle traits using SSR markers. A genetic linkage map was constructed using one hundred fifty four simple sequence repeat ...
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ژورنال
عنوان ژورنال: PLOS Computational Biology
سال: 2020
ISSN: 1553-7358
DOI: 10.1371/journal.pcbi.1007882